Medication-Assisted Treatment (MAT) Treatment Centers

San Francisco AIDS Foundation provides comprehensive substance use treatment and co-occurring mental health services in San Francisco, specializing in care for people with HIV/AIDS and LGBTQ+ communities. Their evidence-based approach combines cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling delivered through flexible outpatient and telehealth options. The foundation is uniquely positioned to address the intersecting health needs of marginalized populations, including survivors of intimate partner violence and sexual abuse.

San Francisco General Hospital in San Francisco offers comprehensive substance use disorder treatment integrated with mental health services for adults and children. Specializing in co-occurring disorders, the hospital provides evidence-based outpatient care including medication-assisted treatment (methadone, buprenorphine, naltrexone) and specialized programs for pregnant/postpartum women and individuals living with HIV/AIDS. As a CARF-accredited and SAMHSA-certified opioid treatment program, it combines clinical excellence with compassionate, accessible care.

Santa Ana Comprehensive Treatment Center provides specialized detoxification and substance use disorder treatment in Santa Ana, California, serving diverse populations including veterans, LGBTQ+ individuals, and those with co-occurring mental health or trauma histories. The center offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and medication-assisted treatment with methadone and buprenorphine through accredited outpatient and detoxification programs. Their specialized tracks address unique needs such as intimate partner violence recovery, pain management with substance use disorders, and criminal justice-involved clients.

Seascape Recovery Center in Watsonville provides comprehensive detoxification and substance use treatment in a supportive residential environment. Specializing in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-related counseling, the center addresses co-occurring mental health and pain disorders alongside addiction. With Joint Commission accreditation and state oversight, Seascape delivers personalized, clinically rigorous care for adults and LGBTQ+ individuals seeking lasting recovery.

Serenity Knolls Treatment Center in Forest Knolls, CA provides comprehensive detoxification and substance use treatment in both short-term and long-term residential settings. Specializing in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-informed care, the center serves diverse populations including veterans, LGBTQ+ individuals, and those with co-occurring mental health or pain disorders. CARF-accredited and state-approved, Serenity Knolls offers integrated support for complex needs including domestic violence recovery and criminal justice-involved clients.

Skyway House Residential in Chico, CA provides comprehensive substance use treatment through evidence-based residential programs ranging from short-term to long-term stays. The facility specializes in integrated approaches including 12-step facilitation, cognitive behavioral therapy, trauma-informed care, and relapse prevention strategies. Licensed by the State Substance Use Treatment Agency, Skyway House combines structured therapeutic environments with personalized counseling to address both addiction and underlying behavioral health concerns.

Siskiyou County HHSA in Yreka provides comprehensive substance use treatment with a focus on evidence-based approaches including motivational interviewing, Matrix Model, and trauma-informed counseling. Serving adolescents through adults, including specialized programs for pregnant and postpartum women, the facility offers flexible care levels from outpatient to intensive outpatient treatment. Accredited by the State Department of Health, they integrate telemedicine options to increase accessibility across rural Siskiyou County.

Service League of San Mateo County in Redwood City provides specialized substance use treatment and co-occurring mental health services for adults and children across multiple residential settings. The organization excels in serving vulnerable populations including trauma survivors, LGBTQ+ individuals, pregnant women, and those involved in the criminal justice system. With evidence-based approaches like cognitive behavioral therapy, motivational interviewing, and trauma-informed care, they address the complex intersections of addiction, mental health, and life circumstances.

San Fernando Recovery Center in San Fernando, CA specializes in comprehensive substance use disorder treatment with a focus on evidence-based recovery approaches. The facility offers hospital inpatient care and long-term residential programs designed for adult men and individuals involved in the criminal justice system seeking structured rehabilitation. With state accreditation and diverse therapeutic modalities including motivational interviewing and relapse prevention, the center provides individualized pathways to sustainable recovery.

San Francisco AIDS Foundation provides compassionate substance use and co-occurring mental health treatment in San Francisco, specializing in care for people living with HIV/AIDS and LGBTQ+ communities. Their evidence-based outpatient programs combine cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling, with telehealth options for flexible access. The foundation is uniquely equipped to serve clients with complex needs including intimate partner violence, sexual abuse histories, and pain management alongside substance use recovery.

Second Chance Inc in Newark, CA specializes in comprehensive substance use treatment with a deep commitment to serving vulnerable and underrepresented populations, including veterans, LGBTQ+ individuals, trauma survivors, and those in the criminal justice system. Their evidence-based approaches—including motivational interviewing, Matrix Model therapy, and trauma-focused counseling—address both addiction and co-occurring mental health conditions. With flexible outpatient and intensive outpatient options plus telemedicine access, they remove barriers to recovery for those who need a genuine second chance.

Second Chance Inc in Hayward, CA specializes in comprehensive substance use disorder treatment with a trauma-informed approach that serves military personnel, veterans, and LGBTQ+ individuals alongside general adult populations. The facility offers intensive and regular outpatient programs utilizing evidence-based methods including motivational interviewing, relapse prevention, and the Matrix Model, with telemedicine options for flexible access. Accredited by California's state substance use treatment agency and department of health, Second Chance addresses co-occurring mental health conditions and supports clients navigating intimate partner violence and sexual abuse recovery.

San Joaquin County Behavioral Health in French Camp provides comprehensive substance use treatment and detoxification services with specialized care for co-occurring mental health conditions. Their evidence-based programs address trauma, domestic violence, and pain-related substance use, serving diverse populations including veterans, LGBTQ individuals, and those involved in the criminal justice system. The facility offers both residential and telehealth options, ensuring accessible care for adults and seniors across the county.

Santa Rosa Treatment Program Inc provides comprehensive substance use disorder treatment in Santa Rosa, CA, specializing in opioid addiction recovery through medication-assisted treatment and evidence-based counseling. The program offers flexible outpatient options including methadone and buprenorphine services, combined with motivational interviewing and trauma-focused therapy to address underlying causes of addiction. Accredited by CARF and certified as a SAMHSA opioid treatment program, they deliver medically supervised care designed for sustainable recovery.

Shasta County Health and Human Services in Redding provides comprehensive substance use treatment with specialized programs for vulnerable populations including pregnant women, trauma survivors, and those with co-occurring disorders. Their evidence-based approaches—including cognitive behavioral therapy, motivational interviewing, and trauma-informed care—are delivered through flexible outpatient and intensive outpatient settings. As a state-accredited agency, they also offer telehealth options to expand access to care across the region.

Skyway House Outpatient in Chico, CA provides comprehensive substance use treatment through flexible outpatient and intensive outpatient programs. Specializing in evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed care, the facility addresses both addiction recovery and underlying behavioral health concerns. State-accredited and focused on relapse prevention, Skyway House supports individuals seeking structured recovery without residential placement.

San Joaquin County Behavioral Health in Stockton provides evidence-based substance use treatment with specialized programs for adolescents, young adults, pregnant women, and forensic clients. The facility offers intensive outpatient and regular outpatient care utilizing proven therapeutic approaches including CBT, motivational interviewing, and trauma-informed counseling. As a state-accredited substance use treatment agency, they combine in-person services with telehealth options for flexible, accessible recovery support.

Sitike Counseling Center in South San Francisco provides comprehensive substance use treatment and dual-diagnosis care for adults and children managing both addiction and serious mental health conditions. Specializing in evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling, the center serves diverse populations including LGBTQ+ clients, veterans, and survivors of intimate partner violence. Both in-person and telehealth options ensure flexible, accessible care for individuals at every stage of recovery.

Sierra County Behavioral Health in Loyalton, CA specializes in comprehensive substance use disorder treatment with integrated mental health services for adults and children. The facility provides evidence-based approaches including motivational interviewing, trauma-informed counseling, and telemedicine options to serve diverse populations from rural communities. As a SAMHSA-certified opioid treatment program, they address co-occurring disorders and support specialized populations including veterans, pregnant women, LGBTQ clients, and those with trauma histories.

Sierra Tribal Consortium Inc in Fresno, CA provides comprehensive substance use treatment through residential and outpatient programs specifically designed for underserved populations including tribal members, veterans, and individuals with complex trauma histories. Their evidence-based approach combines 12-step facilitation, cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling, with transitional housing and sober living options supporting long-term recovery. As a Federally Qualified Health Center, they address co-occurring mental health, chronic pain, and HIV/AIDS alongside addiction treatment.