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Drug & Alcohol Rehab Centers in Santa Ana, California

Discover 15 addiction treatment facilities in Santa Ana. Our comprehensive directory helps you find the right rehabilitation center with 24/7 support available, licensed facilities, and insurance accepted at most locations. Whether you need detox services, residential treatment, outpatient programs, or sober living arrangements, find the perfect match for your recovery journey.

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Cornerstone Adult Outpatient
+9 photos
1950 East 17th Street, 92705
714-547-4300
Cornerstone Adult Outpatient in Santa Ana, CA provides comprehensive substance use disorder treatment with multiple intensity levels, from traditional outpatient to intensive day programs. The facility specializes in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and relapse prevention, with specialized support for co-occurring mental health and pain conditions. Accredited by The Joint Commission and state agencies, Cornerstone serves active duty military, criminal justice clients, and individuals managing complex dual diagnoses.
Substance use treatment
Newport Academy
+9 photos
9951 Highcliff Drive, 92705
877-820-6371
Newport Academy in Santa Ana provides comprehensive substance use treatment and co-occurring mental health care for adolescents and adults through evidence-based approaches. Specializing in trauma-informed care and LGBTQ-affirming services, the facility offers flexible treatment settings from intensive outpatient programs to residential care. With Joint Commission accreditation and state oversight, Newport Academy combines cognitive behavioral therapy, motivational interviewing, and relapse prevention to address complex addiction and mental health challenges.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
12822 Periwinkle Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA specializes in integrated treatment for substance use disorders and co-occurring mental health conditions across multiple care settings. The facility serves adults with serious mental illness and children with serious emotional disturbance, offering evidence-based therapies including CBT, trauma counseling, and relapse prevention. Their accreditation by The Joint Commission and state health department ensures high-quality, comprehensive care tailored to individual recovery needs.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
9881 Deerhaven Drive, 92705
855-272-7451
Newport Institute in Santa Ana, CA provides specialized substance use treatment with integrated mental health care for adults and adolescents experiencing co-occurring disorders. The facility offers flexible treatment settings from intensive outpatient programs to 24-hour residential care, utilizing evidence-based approaches including cognitive behavioral therapy, trauma counseling, and relapse prevention. Their LGBTQ-affirming environment and specialized programs for young adults with trauma histories make them a comprehensive resource for complex cases.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos
10022 Miramar Circle, 92705
855-272-7451
Newport Institute in Santa Ana provides comprehensive substance use and co-occurring mental health treatment for adolescents and adults through multiple levels of care. Specializing in trauma-informed approaches, the facility offers intensive outpatient programs, residential treatment, and partial hospitalization services utilizing evidence-based therapies like cognitive behavioral therapy and motivational interviewing. Joint Commission accreditation ensures high-quality, standards-based care.
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Pacific Sands Recovery Center
+9 photos
1909 West Carlton Place, 92704
844-568-7328
Pacific Sands Recovery Center in Santa Ana, CA provides comprehensive detoxification and substance use treatment with specialized care for co-occurring mental health conditions. The facility offers both hospital inpatient and residential settings, serving diverse populations including veterans, LGBTQ individuals, trauma survivors, and those managing chronic pain alongside addiction. Their evidence-based approach combines 12-step facilitation, cognitive behavioral therapy, trauma counseling, and motivational interviewing to support lasting recovery.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Phoenix House
+9 photos
Phoenix House

Orange County

1207 East Fruit Street, 92701
714-953-9373
Phoenix House in Santa Ana provides comprehensive substance use treatment and detoxification services for diverse populations, including specialized programs for trauma survivors, LGBTQ+ individuals, and pregnant women. Their integrated approach addresses co-occurring mental health and substance use disorders through evidence-based therapies like cognitive behavioral therapy, motivational interviewing, and trauma-focused counseling. With settings ranging from intensive outpatient to long-term residential care, Phoenix House delivers personalized recovery pathways supported by multiple accreditations including CARF, COA, and The Joint Commission.
DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Recovery Homes of America Inc
+9 photos
1950 East 17th Street, 92705
714-567-5345
Recovery Homes of America Inc in Santa Ana, CA provides comprehensive substance use disorder treatment with evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and relapse prevention. The facility serves diverse populations including active duty military, individuals with co-occurring mental health and pain conditions, and those involved in the criminal justice system. Accredited by The Joint Commission and state health authorities, they offer flexible care levels from intensive outpatient to medication-assisted treatment.
Substance use treatment
Santa Ana Comprehensive Treatment Ctr
+9 photos
Santa Ana Comprehensive Treatment Ctr

California Treatment Services LLC

2101 East 1st Street, 92705
714-581-9181
Santa Ana Comprehensive Treatment Center provides specialized detoxification and substance use disorder treatment in Santa Ana, California, serving diverse populations including veterans, LGBTQ+ individuals, and those with co-occurring mental health or trauma histories. The center offers evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and medication-assisted treatment with methadone and buprenorphine through accredited outpatient and detoxification programs. Their specialized tracks address unique needs such as intimate partner violence recovery, pain management with substance use disorders, and criminal justice-involved clients.
DetoxificationSubstance use treatment
Orange County Healthcare Agency
+4 photos
Orange County Healthcare Agency

Behavioral Health Services/SUD

401 West Civic Center Drive, 92701
714-834-3840
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use treatment with specialized programs for adults, pregnant women, and trauma survivors. Their evidence-based approaches include cognitive behavioral therapy, motivational interviewing, relapse prevention, and medication-assisted treatment with methadone, buprenorphine, or naltrexone. The agency excels in treating co-occurring mental health and substance use disorders through flexible outpatient and intensive outpatient settings, plus remote telehealth options.
Substance use treatment
Orange County Healthcare Agency
+4 photos
Orange County Healthcare Agency

Drug Court and DUI Programs

401 West Civic Center Drive, 92701
714-480-6650
Orange County Healthcare Agency in Santa Ana provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and trauma-informed counseling. The facility offers flexible care levels from regular outpatient to intensive outpatient programs, plus medication-assisted treatment with methadone, buprenorphine, and naltrexone. As a state-accredited substance use treatment agency, they combine in-person and telehealth therapy options to support lasting recovery.
Substance use treatment
PES/EBS Inc
600 West Santa Ana Boulevard, 92701
530-888-1010
PES/EBS Inc in Santa Ana provides comprehensive substance use disorder treatment with a focus on evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and the Matrix Model. The facility serves diverse populations, including those involved with the criminal justice system, through flexible care settings ranging from intensive outpatient programs to medication-assisted treatment with methadone, buprenorphine, and naltrexone. Trauma-informed counseling is integrated throughout their treatment offerings.
Substance use treatment
Cooper Fellowship Inc - Placeholder
409 North Cooper Street, 92703
714-554-1152
Cooper Fellowship Inc in Santa Ana, CA provides comprehensive substance use treatment through long-term residential care, addressing the complex needs of diverse populations including military families, trauma survivors, and individuals with co-occurring disorders. The facility specializes in evidence-based approaches such as cognitive behavioral therapy, Matrix Model, and trauma-informed counseling, with dedicated support for LGBTQ+ clients and those experiencing intimate partner violence. As a state-accredited treatment agency, Cooper Fellowship combines 12-step facilitation with modern therapies and telemedicine options to support lasting recovery.
Substance use treatment
Straight Talk Clinics Inc - Placeholder
1225 West 6th Street, 92703
714-972-1402
Straight Talk Clinics Inc in Santa Ana, CA provides comprehensive substance use treatment through evidence-based approaches including cognitive behavioral therapy, motivational interviewing, and the Matrix Model. The clinic specializes in serving diverse populations including LGBTQ individuals, veterans, trauma survivors, and those with co-occurring mental health or pain disorders. With both residential and telehealth options, they offer personalized recovery pathways designed to address each client's unique circumstances and needs.
Substance use treatment
Villa Center Inc - Placeholder
910 North French Street, 92701
714-541-2732
Villa Center Inc in Santa Ana, CA provides comprehensive substance use treatment through both short-term and long-term residential programs. Specializing in evidence-based therapies including cognitive behavioral therapy, motivational interviewing, and trauma-related counseling, the facility serves diverse populations including military members, LGBTQ individuals, and those with co-occurring mental health disorders. Their integrated approach addresses the complex needs of individuals in recovery while maintaining state accreditation across substance use, health, and mental health departments.
Substance use treatment

Addiction Treatment in Santa Ana

Santa Ana is home to a diverse range of addiction treatment facilities, offering comprehensive care for individuals struggling with substance abuse and co-occurring mental health disorders. Whether you're a resident of Santa Ana or traveling for treatment, you'll find quality rehabilitation centers that can help you begin your recovery journey.

Why Choose Treatment in Santa Ana?

  • • Accessibility: Multiple treatment centers throughout the city with various specializations
  • • Quality Care: Licensed and accredited facilities with experienced professionals
  • • Diverse Options: From luxury rehabs to affordable state-funded programs
  • • Support Network: Strong recovery community with numerous support groups
  • • Continuum of Care: Full spectrum from detox to aftercare services

Types of Programs Available

Treatment centers in Santa Ana offer various levels of care to meet different needs:

  • • Medical Detox: Safe, supervised withdrawal management
  • • Inpatient/Residential: 24/7 care in a structured environment
  • • Partial Hospitalization (PHP): Intensive day treatment programs
  • • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • • Standard Outpatient: Weekly therapy and support groups
  • • Sober Living: Transitional housing for ongoing recovery support

Getting Started with Treatment

Finding the right treatment center in Santa Ana starts with understanding your specific needs. Consider factors such as the type of substance use, any co-occurring mental health conditions, insurance coverage, and personal preferences for treatment approach. Many facilities offer free consultations to help you determine the right fit for your recovery journey.